Whole brain apparent diffusion coefficient measurements correlate with survival in glioblastoma patients
نویسندگان
چکیده
منابع مشابه
Apparent Diffusion Coefficient Measures on MR Correlate with Survival in Glioblastoma Multiforme
Introduction: Malignant gliomas are currently evaluated by subjective assessment of T2and contrast-enhanced T1-weighted imaging. Glioblastoma multiforme (GBM) is largely considered a single clinical entity for the purposes of treatment rationalisation, although genetic biomarkers which predict response to treatment in glioma from biopsy samples have been discovered. Non-invasive imaging biomark...
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BACKGROUND AND PURPOSE Patients with traumatic brain injury (TBI) and low Glasgow coma scale (GCS) scores may have severe injury associated with cellular disruption that can be studied with whole-brain apparent diffusion coefficient (ADC) histograms. We retrospectively studied this hypothesis and correlated ADC with GCS. METHODS Twenty-one patients (37.81 +/- 41.3 years) with TBI were enrolle...
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BACKGROUND AND PURPOSE Currently it is difficult to predict tumor response to anti-angiogenic therapy in individual patients. Our aim was to determine if ADC histogram analysis can stratify progression-free and overall survival in patients with newly diagnosed GBM treated "up-front" (ie, before tumor recurrence) with bevacizumab. MATERIALS AND METHODS Up-front bevacizumab-treated and control ...
متن کاملApparent diffusion coefficient measurements in the hippocampi in patients with temporal lobe seizures.
BACKGROUND AND PURPOSE Loss of neurons results in a relative increase in extracellular space that may lead to altered apparent diffusion coefficient (ADC) values in the hippocampi of patients with seizures. Our purpose was to determine if ADC values along the long axis of hippocampi are useful in evaluating patients with partial complex seizures. METHODS Hippocampi of 23 patients with partial...
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This study aimed to evaluate the reproducibility of apparent diffusion coefficient (ADC) measurements in malignant breast masses, and to determine the influence of mammographic parenchymal density on this reproducibility. Sixty-six patients with magnetic resonance findings of the mass were included. Two breast radiologists measured the ADC of the malignant breast mass and the same area on the c...
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ژورنال
عنوان ژورنال: Journal of Neuro-Oncology
سال: 2019
ISSN: 0167-594X,1573-7373
DOI: 10.1007/s11060-019-03357-y